The South Precinct serves as the main office for both the south precinct and the Portland Police Bureau. Captain Sean Renard fills the role of commander of the precinct. The precinct provides office space, evidence storage, and interrogation rooms for the officers. The arson investigators also have offices in the building.
Police press conferences and media briefings are held here.
As is normal for a reasonably sized police establishment, it has several holding cells. These are located in the basement. Notably, there have been 4 deaths in the holdings cells, along with one murdered jailer.
Curiously, however, the interior of the P.P.D. training center in St. Joseph is used for the office where Nick, Hank, Wu, and Renard work.